I got my eSellerate account approved a few days ago and haven’t gotten around to actually setting it up for the website yet. That will be one of my priorities for this weekend. The actual mechanics of getting the product up and running are smooth as silk, and I estimate that I have played around with them for about 4-5 hours and could get a product listed in under 30 minutes if I really wanted to, start to finish. The main difficulty is skinning the site to make it look and feel like your website.
My one complain about eSellerate — the number of pages you have to click through just screams “Abandon this software purchase!”. The lowest I’ve been able to force it to is about 5 steps. Yeah, egads.